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изкушение Лесно да се случи вечно kappa opioid receptor activates stat3 аларма натрупват Всяка година

Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience
Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience

Physiology, signaling, and pharmacology of opioid receptors and their  ligands in the gastrointestinal tract: current concepts and future  perspectives | SpringerLink
Physiology, signaling, and pharmacology of opioid receptors and their ligands in the gastrointestinal tract: current concepts and future perspectives | SpringerLink

Frontiers | An Update on the Multifaceted Roles of STAT3 in the Heart
Frontiers | An Update on the Multifaceted Roles of STAT3 in the Heart

Kappa opioid receptor agonists improve postoperative cognitive dysfunction  in rats via the JAK2/STAT3 signaling pathway
Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathway

κ-opioid receptor activation promotes mitochondrial fusion and enhances  myocardial resistance to ischemia and reperfusion injury via STAT3-OPA1  pathway - ScienceDirect
κ-opioid receptor activation promotes mitochondrial fusion and enhances myocardial resistance to ischemia and reperfusion injury via STAT3-OPA1 pathway - ScienceDirect

Transcriptional activation of human mu‐opioid receptor gene by insulin‐like  growth factor‐I in neuronal cells is modulated by the transcription factor  REST - Bedini - 2008 - Journal of Neurochemistry - Wiley Online Library
Transcriptional activation of human mu‐opioid receptor gene by insulin‐like growth factor‐I in neuronal cells is modulated by the transcription factor REST - Bedini - 2008 - Journal of Neurochemistry - Wiley Online Library

Cells | Free Full-Text | Role of JAK/STAT3 Signaling in the Regulation of  Metastasis, the Transition of Cancer Stem Cells, and Chemoresistance of  Cancer by Epithelial–Mesenchymal Transition | HTML
Cells | Free Full-Text | Role of JAK/STAT3 Signaling in the Regulation of Metastasis, the Transition of Cancer Stem Cells, and Chemoresistance of Cancer by Epithelial–Mesenchymal Transition | HTML

Molecular mechanisms of opioid receptor-dependent signaling and behavior. -  Abstract - Europe PMC
Molecular mechanisms of opioid receptor-dependent signaling and behavior. - Abstract - Europe PMC

Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic  Targets: Recent Progress and Future Perspective
Frontiers | Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic Targets: Recent Progress and Future Perspective

Opioids drive breast cancer metastasis through the δ-opioid receptor and  oncogenic STAT3 - ScienceDirect
Opioids drive breast cancer metastasis through the δ-opioid receptor and oncogenic STAT3 - ScienceDirect

Non-canonical Opioid Signaling Inhibits Itch Transmission in the Spinal  Cord of Mice
Non-canonical Opioid Signaling Inhibits Itch Transmission in the Spinal Cord of Mice

PDF) Enhancing Remyelination through a Novel Opioid-Receptor Pathway
PDF) Enhancing Remyelination through a Novel Opioid-Receptor Pathway

Opioid receptors beyond pain control: The role in cancer pathology and the  debated importance of their pharmacological modulation - ScienceDirect
Opioid receptors beyond pain control: The role in cancer pathology and the debated importance of their pharmacological modulation - ScienceDirect

Non-canonical Opioid Signaling Inhibits Itch Transmission in the Spinal  Cord of Mice
Non-canonical Opioid Signaling Inhibits Itch Transmission in the Spinal Cord of Mice

κ-opioid receptor activation promotes mitochondrial fusion and enhances  myocardial resistance to ischemia and reperfusion injury via STAT3-OPA1  pathway - ScienceDirect
κ-opioid receptor activation promotes mitochondrial fusion and enhances myocardial resistance to ischemia and reperfusion injury via STAT3-OPA1 pathway - ScienceDirect

Welcome to Scientific Archives | A Brief Update on STAT3 Signaling: Current  Challenges and Future Directions in Cancer Treatment
Welcome to Scientific Archives | A Brief Update on STAT3 Signaling: Current Challenges and Future Directions in Cancer Treatment

Constitutively Active Gα16 Stimulates STAT3 via a c-Src/JAK- and  ERK-dependent Mechanism* - Journal of Biological Chemistry
Constitutively Active Gα16 Stimulates STAT3 via a c-Src/JAK- and ERK-dependent Mechanism* - Journal of Biological Chemistry

Down-regulation of kappa opioid receptor promotes ESCC proliferation,  invasion and metastasis via the PDK1-AKT signaling pathway | Cell  Communication and Signaling | Full Text
Down-regulation of kappa opioid receptor promotes ESCC proliferation, invasion and metastasis via the PDK1-AKT signaling pathway | Cell Communication and Signaling | Full Text

Opioids in cancer: The κ‑opioid receptor (Review)
Opioids in cancer: The κ‑opioid receptor (Review)

Functional independence of endogenous μ- and δ-opioid receptors  co-expressed in cholinergic interneurons | eLife
Functional independence of endogenous μ- and δ-opioid receptors co-expressed in cholinergic interneurons | eLife

Regulation of STAT3 and its role in cardioprotection by conditioning: focus  on non-genomic roles targeting mitochondrial function | SpringerLink
Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function | SpringerLink

Molecular mechanisms of opioid receptor-dependent signaling and behavior. -  Abstract - Europe PMC
Molecular mechanisms of opioid receptor-dependent signaling and behavior. - Abstract - Europe PMC

Scheme of the activation on the RISK pathway induced by d - and k... |  Download Scientific Diagram
Scheme of the activation on the RISK pathway induced by d - and k... | Download Scientific Diagram

Cytoprotective effect of δ-opioid receptor (DOR) activation in MSC. (A)...  | Download Scientific Diagram
Cytoprotective effect of δ-opioid receptor (DOR) activation in MSC. (A)... | Download Scientific Diagram

gp130/STAT3 signaling is required for homeostatic proliferation and  anabolism in postnatal growth plate and articular chondrocytes |  Communications Biology
gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes | Communications Biology

Signal Transducer and Activator of Transcription 3 Activation by the δ-Opioid  Receptor via Gα14 Involves Multiple Intermediates | Molecular Pharmacology
Signal Transducer and Activator of Transcription 3 Activation by the δ-Opioid Receptor via Gα14 Involves Multiple Intermediates | Molecular Pharmacology